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The authors present case reports of two young women, who visited the outpatient Department of Ophthalmology clinic, University Hospital in Hradec Králové with lacklustre subjective eye complaints lasting over few weeks. It the beginning high values of intraocular pressure in both eyes and severe glaucomatous damage of the optic nerve head were find out, which was confirm using perimetry and OCT (o...

Aim: To provide a survey of the current clinical use of intraoperative optical coherence tomography (iOCT), especially in the context of our own vitreo-retinal experience. Methods: Retrospective evaluation of casuistic cases of typical diseases of the retina, which were treated by standard pars plana vitrectomy (PPV) using iOCT integrated into an operating microscope OPMI Lumera 700 / Rescan 700 (...

The review points to the issues of persistent hyaloid artery, more precisely to possible clinical features, the influence on visual functions and potential complications during intraocular surgeries. In professional journals we can find just few reviews regarding this rare deviation of the eye development, therefore we want to present our experience. The persistent hyaloid artery causes chronical ...

Purpose: To evaluate anatomical, functional and clinical efficacy of the pattern scanning laser (PASCAL®) photocoagulation in patients with diabetic retinopathy. Methods: The cohort included 91 eyes in 50 patients (average age 63 years, 24 men and 26 women) treated at the Clinic of Ophthalmology, Faculty Hospital Ostrava, from 2008 to 2013. All eyes showed the signs of diabetic retinopathy (20.9% ...

Progress in optical coherent tomography (OCT) has recently provided new insights into variety of chorioretinal disorders. The use of EDI (Enhanced Depth Imaging) during OCT examinations and as well as OCT angiography provides a more accurate analysis of the choroid both quantitatively and qualitatively. „Pachychoroid“ (greek pachy- [παχύ]: thick) is defined as an abnormal and sustained increase in...

Punctate Inner Choroidopathy (PIC) is a rare idiopathic ocular inflammatory disease. It occurs mostly in young, myopic, otherwise healthy women. Symptoms of the disease include acute vision decrease associated with central and paracentral scotoma. In 80% of cases PIC occur bilaterally. We report the case of a woman at the age of twenty-five, who was treated for PIC. Due to the finding of active in...

Introduction: Diabetic macular edema (DME) is the most frequent cause of decreased vision in patiens with diabetes type 2. DME is caused by increased permeability of macular capillaries. The aim of our study was to retrospectively evaluate the results of micropulse laser treatment, 577 nm wavelength, in pacients with DME with follow-up three months and one year. Methods: The retrospective trial wi...

Background and aims: To determine the incidence of ocular pathological findings in a group of patients with acute leukemia. To define the predictive value of the presence of the ocular pathological findings. Materials and methods: Retrospective evaluation of a group of 67 patients with acute leukemia (age 1–75 years) examined at the Ophthalmology Clinic, Faculty Hospital Ostrava, from 2005 to 2014...

Background: Cataract surgery is one of the most common procedures performed by the ophthalmic surgeon. In this paper, we evaluate of postoperative results of the hydrophobic intraocular lens CT LUCIA 611 in patients undergoing routine cataract surgery. Methods: The study included 23 patients (29 eyes), average age of 69.0 + 9.2 years (span 53 to 86 years) with uncomplicated senile cataract. After ...

Pachychoroid disease of the macula includes four stages: pachychoroid pigment epitelopathy, central serous chorioretinopathy, pachychoroid neovasculopathy, and polypoid choroidal vasculopathy. Their basic common features are increase in choroidal thickness ≥ 300 μm, pathologically dilated choroidal vessels in the Haller’s layer with thinning of Sattle's layer and choriocapillaris layer. We report ...

Background and aims: To evaluate the characteristics and incidence of ophthalmic manifestations in patients with HIV (Human Immunodeficiency Virus) infection. Materials and methods: A retrospective evaluation of medical records of 147 patients with HIV infection (22 female, 125 male), the average age of 41 (range 22–79 years) examined by an ophthalmologist at the Clinic of Ophthalmology at the Uni...

Purpose: To evaluate the safety and clinical efficacy of ranibizumab (Lucentis) in the treatment of choroidal neovascularization (CNV) caused by diseases other than age-related macular degeneration (AMD). Patients: 21 patients with mean age 61 ± 17.2 years (min 16, max 85) with CNV due to causes other than AMD, in particular pathological myopia (n=11), angioid streaks (n=3), central serous chorior...

Purpose: To retrospectively evaluate the efficacy and safety of ranibizumab treatment for macular edema (ME) secondary to branch retina vein occlusion(BRVO) after 24 months. Materials and Methods: This study included 39 eyes of 39 patients with ME associated with BRVO treated at the Ophthalmology Department of Faculty Hospital in Hradec Kralove. The average age of included patiens was 69,3 years, ...

The authors present case reports of two women, who were hospitalized in Department of Ophthalmology, University hospital Hradec Králové for ocular symptoms of rosacea. In the beginning there were relatively severe objective findings in the anterior segment of the eye in both cases – significant cornea graying with superficial and deep cornea vascularization in both eyes. On faces of both patients ...

Aim: To compare parameters of phacoemulsification using handpiece Active Sentry and Centurion Ozil. Methods: We have evaluated results of 200 eyes of 129 patients that were operated for cataract at the Department of Ophthalmology. All surgeries were performed by one surgeon (NJ). In 100 eyes handpiece Active Sentry was used and in 100 eyes handpiece Centurion Ozil was used. The intraocular pressur...

Aims: Present the use of Optical Coherence Tomography Angiography (OCTA) in vitreoretinal interface diseases and results of macular capillary network evaluation before and after idiopathic macular hole surgery (IMD). Methodology: Prospective evaluation of functional results, anatomical and OCTA findings before and after IMD surgery. The group consists of 8 eyes of eight patients. Preoperatively an...

Aim: To evaluate, on the basis of two-year observations, the effectiveness of intravitreal treatment with Ranibizumab in patients with diabetic macular edema (DME) unresponsive to the previous laser treatment. Cohort and Methods: A retrospective study evaluates 29 eyes of 29 patients with diffuse DME unresponsive to their previous laser treatment. The group of the patients consisted of 16 males (5...

Aim: Presentation of the 1-year results of aflibercept treatment in patients suffering from diabetic macular edema (DME) and comparison of the response to treatment of patients with different baseline central retinal thickness (CRT). Methods: This was a multicentre, retrospective observational study of a series of cases. Patients with DME were treated in a fixed regimen (5 injections at 1-monthly ...

Purpose: Evaluation of the long-term effect of rheopheresis treatment of dry form of age-related macular degeneration (AMD). Materials and Methods: The treatment group consisted of 65 patients and 55 patients in the control group, with a minimum follow-up period of 60 months. The basic treatment consisted of 8 rheopheresis procedures, and the additional treatment (booster therapy) of 2 rheopheresi...

Aim: We present a case report of a patient with dry form of age-related macular degeneration (AMD) in whom we monitored the effect of rheohemapheresis (RhF) treatment over 6 years. Methods: A 67-year-old man was examined in April 2014 at the Department of Ophthalmology at the University Hospital in Hradec Králové for metamorphopsia and decreased visual acuity of the left eye. The patient received ...

Introduction: The term "pachychoroid" (greek pachy- [παχύ] - thick) was first used by Warrow et al. in 2013. It is defined as an abnormal and permanent increase in choroidal thickness ≥ 300 μm, which is caused by dilatation of the choroidal vessels of the Haller's layer, thinning of the Sattler's layer and the choriocapillaris layer. Methodology: Literary research focused on the current view of pa...