The authors present case reports of two young women, who visited the outpatient Department of Ophthalmology clinic, University Hospital in Hradec Králové with lacklustre subjective eye complaints lasting over few weeks. It the beginning high values of intraocular pressure in both eyes and severe glaucomatous damage of the optic nerve head were find out, which was confirm using perimetry and OCT (optical coherence tomography). The anamnesis has shown that both patients have been treated for atopic eczema since their childhood. Theskin disease is controlled by local application of corticosteroids preparations. The aim of this report is to highlight the issue of steroid induced glaucoma during local steroid therapy of chronical skin diseases with the maximum of expression in the face. Wrong and long-term using of corticosteroids can lead to the distinct and permanent reduction of visual field or even the loss of vision. The relevance of this eye disease is also depends on the initial, inconspicuous development of eye complaints. However, regular ophthalmology checks can prevent serious deteriorating of visual functions in patients with steroid therapy.